Recent publications

1. Stanne, T., Narayanan, M.S., Ridewood, S., Ling, A., Witmer, K., Kushwaha, M., Wiesler, S., Wickstead, B., Wood, J. and Rudenko, G. (2015)  Identification of the ISWI chromatin remodeling complex of the early branching eukaryote Trypanosoma brucei. Journal of Biological Chemistry 290 (45): 26594-26967.

2. Denninger, V and Rudenko G. (2014) FACT plays a major role in histone dynamics affecting VSG expression site control in Trypanosoma brucei. Mol Microbiology 94(4): 945-962.

3. Ooi C.P. and Rudenko G. (2014) Do trypanosome turncoats wait before they commit? Elife 2014 Jun 3, 3:e03176.

4. Narayanan M.S. and Rudenko G. (2013)  TDP1 is an HMG chromatin protein facilitating RNA polymerase I transcription in African trypanosomes. Nucleic Acids Research 41(5): 2981-2992.

5. Povelones M.L., Gluenz, E., Dembek, M., Gull, K. and Rudenko G. (2012)  Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei. PLoS Pathogens 8(11): e1003010.

6. Vink, C., Rudenko, G. and H. S. Seifert. (2012)  Microbial antigenic variation mediated by homologous DNA recombination. FEMS Microbiol Rev. 2012 Dec 25.

7. Rudenko, G. (2011)  African trypanosomes: the genome and adaptations for immune evasion. Essays in Biochemistry 51: 47-62.

8. Stanne, T., Kushwaha, M., Wand, M., Taylor, J.E. and Rudenko, G. (2011)  TbISWI regulates multiple Polymerase I (Pol I)- transcribed loci and is present at Pol II transcription boundaries in Trypanosoma brucei. Eukaryotic Cell 10(7): 964-976.  Subject of a Spotlight: article of significant interest selected by the editors. Eukaryotic Cell 10(7): p. 855.

9. Narayanan, M., Kushwaha, M., Ersfeld, K., Fullbrook, A., Stanne, T.M. and Rudenko, G. (2011) NLP is a novel transcription regulator involved in VSG expression site control in Trypanosoma brucei. Nucleic Acids Research 39(6) 2018-2031.

10. Rudenko, G. (2010)  Epigenetics and transcriptional control in African trypanosomes.  Essays in Biochemistry 48(1): 201-219.

11. Denninger, V., Fullbrook, A., Bessat, M., Ersfeld, K. and Rudenko, G. (2010)  The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei.  Molecular Microbiology 78(2): 459-474.

12. Stanne, T. and Rudenko G. (2010) Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes. Eukaryotic Cell 9 (1): 136-147. Subject of a Spotlight: article of significant interest selected from this issue by the editors. Eukaryotic Cell 9 (1): p 21. Selected as a research highlight Nature Reviews Microbiology 8 (3): 160

13. Smith, T.K., Vasileva, N., Gluenz, E., Terry, S., Portman, N., Kramer, S., Carrington, M., Michaeli, S., Gull, K. and Rudenko G. (2009) Blocking Variant Surface Glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation. PLoS ONE 4(10):e7532.

14. Young R, Taylor JE, Kurioka A, Becker M, Louis EJ, and Rudenko G. (2008) Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum. BMC Genomics 9: 385.

15. Hughes K., Wand M, Foulston L, Young R, Harley K, Terry S, Ersfeld K and Rudenko G (2007) A novel ISWI is involved in VSG expression site downregulation in African trypanosomes. EMBO J 26: 2400-2410.

16. Taylor J.E. and Rudenko G. (2006) Switching trypanosome coats: what's in the wardrobe? Trends in Genetics 22: 614-620.

17. Rudenko G. (2005) Maintaining the protective variant surface glycoprotein coat of African trypanosomes. Biochem Soc Trans. 33: 981-2.

18. Aitcheson, N., Talbot, S., Shapiro, J., Hughes, K., Adkin, C., Butt, T., Sheader, K. and Rudenko G. (2005) VSG switching in Trypanosoma brucei: antigenic variation analysed using RNAi rather than an immune system. Molecular Microbiology 57: 1608-1622.

19. Sheader, K., Vaughan, S., Minchin, J., Hughes, K., Gull, K. and Rudenko G. (2005) Variant Surface Glycoprotein RNAi triggers a precytokinesis cell cycle arrest in African trypanosomes. Proceedings of the National Academy of Sciences USA 102: 8716-8721. (Covered in Editors' choice: Science (2005) 308: 1843).

20. Becker M., Aitcheson N., Byles E., Wickstead, B., Louis E. and Rudenko G. (2004) Isolation of the repertoire of VSG expression site containing telomeres of Trypanosoma brucei 427 using Transformation Associated Recombination in yeast. Genome Research 14: 2319-2329.

21. Sheader K., te Vruchte, D. and Rudenko G. (2004) Bloodstream form specific upregulation of VSG expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage. Journal of Biological Chemistry 279: 13363-13374.